Table 1.
Codon mutation | Nucleotide change | No. of strains | ||||
---|---|---|---|---|---|---|
MIC (mg/L) | ||||||
2 | 4 | 8 | 16 | 32 | ||
D94A | GAC-GCC | 4 | 2 | 1 | ||
D94G | GAC-GGC | 5 | 10 | 10 | 3 | 3 |
D94N | GAC-AAC | 2 | 2 | 2 | 1 | |
D94Y | GAC-TAC | 1 | 3 | 4 | ||
D94F | GAC-TTC | 1 | ||||
A90V | GCG-GTC/GTG | 6 | 10 | 7 | 1 | |
S91P | TCG-CCG | 2 | 2 | 2 | ||
A90V&D94Y | GCG-GTC & GAC-TAC | 1 |