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The patterns of gyrA mutations and OFX MICs profile of OFX-resistant MTB strains
| Codon mutation | Nucleotide change | No. of strains | ||||
|---|---|---|---|---|---|---|
| MIC (mg/L) | ||||||
| 2 | 4 | 8 | 16 | 32 | ||
| D94A | GAC-GCC | 4 | 2 | 1 | ||
| D94G | GAC-GGC | 5 | 10 | 10 | 3 | 3 |
| D94N | GAC-AAC | 2 | 2 | 2 | 1 | |
| D94Y | GAC-TAC | 1 | 3 | 4 | ||
| D94F | GAC-TTC | 1 | ||||
| A90V | GCG-GTC/GTG | 6 | 10 | 7 | 1 | |
| S91P | TCG-CCG | 2 | 2 | 2 | ||
| A90V&D94Y | GCG-GTC & GAC-TAC | 1 | ||||
