Figure 5. Tumor size in Cd34^−/− surpasses Cd34^+/+ by day 19, due to hematopoietic loss of CD34.

A, Average s.c.-injected tumor masses 19 days post-injection in Cd34^+/+ and Cd34^−/− animals. (Pooled from three experiments, Cd34^+/+ n = 15, Cd34^−/− n = 16). B, Average tumor mass at day 19 in wildtype Ly5.1 animals reconstituted with either Cd34^+/+ or Cd34^−/− bone marrow. (Pooled from two experiments, Cd34^+/+ into Ly5.1 n = 11, Cd34^−/− into Ly5.1 n = 13). (*represents p<0.05; Error bars = SEM).