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The pSIN-β plasmid was no longer more effective than pCMV-β against tumors in athymic mice. Mice (n = 6-8) were s.c. implanted with TC-1 tumor cells (5 × 105) on day 0. From days 4 to 13, mice were injected (s.c., p.t) with lipoplexes prepared with pSIN-β (25 μg) or pCMV-β (25 μg).
