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. 2011 Apr 11;6(4):e18559. doi: 10.1371/journal.pone.0018559

Table 1. Induction of memory B cell responses following vaccination with RTS,S/AS01E and RTS,S/AS02D (ATP cohort for immunogenicity - B cell subset).

RTS,S/AS01E RTS,S/AS02D RTS,S/AS01E vs RTS,S/AS02D comparison
N Median (Q1–Q3) N Median (Q1–Q3) p-value
Pre 17 0 (0–20) 23 0 (−49–0) 0.12
Month 2 31 1692 (345–4997)*** 28 183 (0–1429)*** 0.013
Month 3 29 1330 (466–2857)*** 32 1795 (662–3204)*** 0.38
Month 14 25 27 (0–2451)* 27 829 (25–1637)*** 0.2

Footnote: Number of CS-specific spots per million total IgG-positive cells are presented.

*p<0.05.

***p<0.001, statistically significant differences against pre-vaccination values.