Table 1. Cardiac function of isolated rat hearts perfused with 0 (n = 8), 0.05 (n = 5), 0.1 (n = 10), 1 (n = 4), 5 (n = 8) and 10 mM (n = 7) glucosamine for 60 minutes (hearts were paced at 320 beats/min rate).
| Glucosamine concentration (mM) | ||||||
| 0 | 0.05 | 0.1 | 1 | 5 | 10 | |
| RPP (mmHg/min×10−3) | 29.1±1.0 | 33.2±2.3 | 28.0±1.1 | 29.8±2.4 | 28.7±1.5 | 31.1±1.3 |
| +dp/dt (mmHg/s×10−3) | 4.1±0.2 | 4.1±0.3 | 3.5±0.1 | 4.0±0.4 | 3.6±0.2 | a3.6±0.2 |
| −dp/dt (mmHg/s×10−3) | 2.1±0.1 | 2.2±0.2 | 1.8±0.1 | 2.0±0.2 | 1.9±0.1 | 2.1±0.3 |
| Coronary flow (ml/min) | 11.5±0.8 | 12.2±0.6 | 11.1±0.4 | 11.5±0.7 | 12.5±0.6 | 13.5±0.9 |
Glucosamine had no effect either on cardiac or on coronary flow. (RPP: rate pressure product = left ventricular developed pressure×heart rate; dp/dt: change of pressure over time).