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. 2011 Apr 11;6(4):e18720. doi: 10.1371/journal.pone.0018720

Figure 5. IFN-γ controls parasite biomass and IRBC accumulation in organs.

Figure 5

(A) Survival and (B) parasitemia of WT and IFN-γ−/− mice (5 mice per group) infected with PbAluc. Parasitemia (%) values are expressed as mean ± SD. In vivo bioluminescence imaging quantification of IRBC accumulation in the whole body (C) and head (D) of WT and IFN-γ −/− mice. Luminescence values (log) as mean ± SD of 5 mice. Ex vivo quantification by bioluminescence imaging of IRBC accumulation in spleens (E) and brains (F) of perfused WT and IFN-γ−/− mice obtained at day 7 and 8 post-infections. Luminescence values (log) as mean ± SD of 5 mice. #p<0.01, log-rank test; *p<0.05, Mann Whitney test; *p<0.05, ANOVA followed by Bonferroni test.