Table 6.
Cognitive test performance as a function of cytokine levels.
| β | p | Adjusted R2 | p | |
|---|---|---|---|---|
| Grooved Pegboard Worse Hand | 0.08 | 0.01 | ||
| IL-16 | −0.08 | 0.01 | ||
|
| ||||
| Stroop Interference | 0.34 | <0.0001 | ||
| IL-18 | 0.09 | 0.0004 | ||
| MCP-1 | 0.02 | 0.007 | ||
| MIP-1β | −0.03 | 0.044 | ||
| TNF-α | 2.02 | 0.003 | ||
|
| ||||
| Trail Making Test A | 0.31 | <0.0001 | ||
| IL-10 | 0.42 | 0.001 | ||
| IL-16 | −0.14 | <0.0001 | ||
| IP-10 | −0.006 | 0.003 | ||
|
| ||||
| Trail Making Test B | 0.39 | <0.0001 | ||
| IL-10 | 0.36 | 0.01 | ||
| IL-16 | −0.06 | 0.04 | ||
|
| ||||
| WAIS-III Digit Symbol-Coding | 0.43 | <0.0001 | ||
| IFN-γ | −1.82 | 0.02 | ||
| IL-1β | 2.34 | 0.04 | ||
| IL-10 | 0.26 | 0.04 | ||
| IL-16 | −0.06 | 0.007 | ||
| IL-18 | 0.07 | 0.008 | ||
| IP-10 | −0.003 | 0.02 | ||
|
| ||||
| WAIS-III Letter-Number Sequencing | 0.25 | 0.0009 | ||
| IL-10 | 0.38 | 0.003 | ||
| TRAIL | 0.23 | 0.02 | ||
|
| ||||
| WAIS-III Symbol Search | 0.23 | 0.002 | ||
| IP-10 | −0.004 | 0.02 | ||
| TRAIL | 0.23 | 0.05 | ||
Regression models selected using Akaike’s information criterion. Demographic, clinical, and cytokine variables were entered as predictors; only cytokines selected in the final model with p <.05 are reported. Adjusted R2 values are for the whole model fit. Abbreviations: WAIS-III, Wechsler Adult Intelligence Scale-Third Edition; Stroop, Stroop Color and Word Test; Cytokine abbreviations: See Table 3.