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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Neurobiol Aging. 2010 Nov 12;33(7):1148–1155. doi: 10.1016/j.neurobiolaging.2010.09.026

Table 3.

Hippocampal and brain volumes in MA and OA cohorts

MA cohort OA cohort
Decline Improve Stable Decline Improve Stable
Hippocampus 7.4 (0.5) 7.3 (0.7) 7.4 (0.7) 6.2 (0.8) 7.1 (0.4)a 6.6 (0.8)
Total brain 1126 (46) 1128 (45) 1129 (41) 1050 (88) 1068 (35) 1070 (52)
Hipp/brain (%) 0.65 (.04) 0.65 (.05) 0.65 (.05) 0.59 (.07) 0.66 (.03)b 0.62 (.06)

Volumes are in cm3 (SD) and have been corrected for ICV via regression (see methods).

a

3 midlife memory status × 2 age cohort ANOVA; memory status × age cohort interaction (F2,78 = 4.1 p < 0.05), Bonferroni corrected t-tests: OA improve > OA decline p < 0.05, OA improve > OA stable p < 0.05. No significant differences within the MA cohort or between MA groups and OA improvers.

b

3 midlife memory status × 2 age cohort ANOVA; memory status × age cohort interaction (F2,78 = 5.1 p < 0.01), Bonferroni corrected t-tests: OA improve > OA decline, p < 0.01, OA improve > OA stable, p < 0.01, No significant differences within the MA cohort or between MA groups and OA improvers.

see Table 1 for abbreviations.