Table 3.
Adjusted Mean Disorder-Specific Outcome Scores by Comorbid Anxiety Disorders
| Intervention | Usual Care | Difference(95% CI) | P Value | Effect Size Difference |
|
|---|---|---|---|---|---|
| GADS SCALE (GAD N = 207,171,159,162) | |||||
| Baseline | 14.72(14.06 to 15.38) | 14.78(14.00 to 15.56) | −0.06(−1.08 to 0.97) | 0.911 | −0.01(−0.22 to 0.20) |
| 6 mo | 9.74(8.80 to 10.69) | 10.91(9.76 to 12.07) | −1.17(−2.67 to 0.33) | 0.389 | −0.24(−0.54 to 0.07) |
| 12 mo | 9.18(8.23 to 10.14) | 10.37(9.17 to 11.56) | −1.18(−2.71 to 0.35) | 0.389 | −0.24(−0.55 to 0.07) |
| 18 mo | 8.92(7.95 to 9.88) | 9.59(8.40 to 10.78) | −0.67(−2.20 to 0.86) | 0.781 | −0.18(−0.60 to 0.24) |
| PDSS SCALE (PD N = 213,185,165,162) | |||||
| Baseline | 12.73(11.58 to 13.88) | 13.22(12.05 to 14.38) | −0.49(−2.14 to 1.17) | 0.563 | −0.09(−0.38 to 0.21) |
| 6 mo | 6.84(5.64 to 8.05) | 8.46(7.22 to 9.70) | −1.62(−3.37 to 0.13) | 0.210 | −0.25(−0.52 to 0.02) |
| 12 mo | 5.45(4.11 to 6.79) | 7.41(6.04 to 8.78) | −1.96(−3.90 to −0.02) | 0.191 | −0.33(−0.65 to 0.00) |
| 18 mo | 4.73(3.54 to 5.91) | 5.97(4.76 to 7.18) | −1.24(−2.97 to 0.48) | 0.312 | −0.21(−0.50 to 0.08) |
| SPIN SCALE (SAD N = 271,236,207,203) | |||||
| Baseline | 37.31(35.10 to 39.52) | 36.26(34.06 to 38.46) | 1.05(−2.08 to 4.18) | 0.510 | 0.07(−0.15 to 0.29) |
| 6 mo | 25.29(22.67 to 27.92) | 29.55(26.97 to 32.14) | −4.26(−7.96 to −0.56) | 0.048 | −0.29(−0.55 to −0.04) |
| 12 mo | 21.14(18.50 to 23.78) | 29.26(26.66 to 31.86) | −8.12(−11.84 to −4.40) | <.001 | −0.55(−0.80 to −0.30) |
| 18 mo | 20.35(17.73 to 22.96) | 26.57(24.01 to 29.13) | −6.23(−9.90 to −2.55) | 0.003 | −0.48(−0.77 to −0.20) |
| PCLC SCALE (PTSD N = 120,102,91,92) | |||||
| Baseline | 55.27(51.87 to 58.67) | 55.48(52.21 to 58.75) | −0.21(−5.03 to 4.61) | 0.932 | −0.01(−0.30 to 0.28) |
| 6 mo | 41.97(37.78 to 46.15) | 47.64(43.46 to 51.83) | −5.67(−11.69 to 0.34) | 0.256 | −0.33(−0.68 to 0.02) |
| 12 mo | 41.00(36.14 to 45.87) | 45.19(40.35 to 50.04) | −4.19(−11.14 to 2.76) | 0.705 | −0.28(−0.73 to 0.18) |
| 18 mo | 40.07(35.33 to 44.82) | 42.32(37.58 to 47.06) | −2.24(−9.04 to 4.55) | 0.932 | −0.18(−0.71 to 0.36) |
Intervention by Time effects based on the WALD test were significant for SPIN at p <.0001.
All p-values come from the longitudinal models (e.g., given the estimates of the longitudinal model we obtained the predicted means at the four time points by intervention group and tested their difference at every time point using the correct t-test).
Data are presented as adjusted mean (95% confidence interval)
Models control for site, age, ethnicity, and number of chronic medical conditions.