Table 1.

Diagnosis, clinical manifestations and number of episodes of upper and lower respiratory tract infections in our cohort of patients with recurrent respiratory tract infections (RRTIs) before and after Bactek® treatment (BT)

Patients	Diagnosis	Clinical manifestations	Episodes before Bactek® (pre-BT)	Episodes after Bactek® (post-BT)
1	RRTIs	Pneumonia	3	0
2	RRTIs Mild hypogammaglobulinaemia	Pharyngitis, tonsillitis and bronchitis	2	0
3	RRTIs	Severe pharyngitis and tonsillitis	8	0
4	RRTIs	Pneumonia	3	0
5	RRTIs	Bronchitis	5	0
6	RRTIs IgA immunodeficiency	Pharyngitis	8	1
7	RRTIs	Otitis and sinusitis	5	0
8	RRTIs IgG4 immunodeficiency	Pneumonia	2	0
9	RRTIs	Severe pharyngitis and tonsillitis	5	1
10	COPD Mild hypogammaglobulinaemia	Pharyngitis and exacerbations of COPD Pneumonia	8 2	1 0
11	RRTIs Mild hypogammaglobulinaemia	Pharyngitis	4	0
12	RRTIs Bronchiectasis	Pharyngitis and tonsillitis Pneumonia	5 2	0 0
13	RRTIs	Sinusitis, otitis and bronchitis	5	0
14	RRTIs Autoimmune thyroiditis	Pharyngitis and tonsillitis	6	0
15	RRTIs IgG4 immunodeficiency	Tonsillitis, pharyngitis and otitis	5	0
16	RRTIs Mild hypogammaglobulinaemia	Bronchitis	5	0
17	RRTIs	Pharyngitis and tonsillitis Labial and nasal HSV infection	10 12	0 3

Pre-BT: number of episodes of upper and lower respiratory tract infections scored 1 year prior to immunization with Bactek®; post-BT: number of episodes of upper and lower respiratory tract infections scored throughout 12 months after initiation of therapy with Bactek®. RRTIs, recurrent respiratory tract infections; HSV, herpes simplex virus; COPD, chronic obstructive pulmonary disease; HSV, herpes simplex virus; Ig, immunoglobulin.