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. 2008 Mar 1;3(1):23–33. doi: 10.4176/071110

Table 3.

The key points about the mechanism of antioxidant effects of garlic

  • Scavenging ROS, inhibiting LDL oxidation

  • Protection of endothelial cell integrity by inhibition of lipid peroxidation induced injury

  • Inhibits homocysteine thiolactone formation

  • Enhancement of cellular reduced glutathione levels (GSH)

  • Enhancement of cellular scavenging enzymes such as superoxide dismutase (SOD) catalase (CAT) and glutathione peroxidase (GPx)

  • Inhibition of nuclear factor- κB activation

  • Modulating neurobehavioral changes in reversible focal ischemia and reperfusion induced cerebral injury by virtue of its antioxidant properties