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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Clin Cancer Res. 2011 Mar 29;17(7):1947–1955. doi: 10.1158/1078-0432.CCR-10-1730

TABLE 3.

Disease Type by Sample Size, Time-to-First Patient, Incidence, and Mortality

Disease Site # of Trials in Sample Time to First Patient (months) IRQ (months) Min-Max (months) Incidences (per 100,000) Mortality (per 100,000 cases)
Gastrointestinal (including colon and pancreas) 119 2 1–4 1–12 84.4 43.5
Lung, Mediastinal and Pleural 86 3 2–4 1–8 63.9 54.1
Miscellaneous Neoplasm 75 2 1–4 1–19 19.7 13.4
Leukemia 64 2 2–2 1–13 12.3 7.4
Breast 58 2 1–3.25 1–22 126.1 25
Female Reproductive 57 3 1–4 1–16 47.3 15.9
Skin 46 2 1–3 1–10 21.1 3.5
Lymphoma 44 4 2.25–5.75 1–18 22.2 7.8
Central Nervous System 41 3 1.5–4 1–14 6.5 4.4
Male Reproductive (including prostate) 36 3.5 1.25–6 1–16 168.4 27
Kidney 36 2 1–3 1–22 13.2 4.2
Head and Neck 35 3 2–5 1–14 14 3.9
Urothelial Tract 18 4 2–5.25 1–11 21.2 4.3
Soft Tissue 17 3 2–5.5 1–12 3.1 1.3
Myeloma 13 3 1.5–3.5 1–7 5.6 3.7
Endocrine 7 2 1–2 1–2 9.8 0.8
AIDS-related 5 5 1–10.5 1–12 1.2 n/a
Bone 2 2.5 2–3 2–3 0.9 0.9
Immune Disorder 2 4.5 4–5 4–5 0.7 0.8
Germ Cell 2 1.5 1–2 1–2 0.4 0.2