. Author manuscript; available in PMC: 2012 Mar 29.

Published in final edited form as: Biochemistry. 2011 Feb 18;50(12):2339–2356. doi: 10.1021/bi1014453

Table 1.

Composition of Peptide Libraries Used in this Work

Library No.	Library Design	Amino Acid Composition at Random Positions (X)
I	SAXXXXXpYAABBRM	Ala, Arg, Asn, Asp, F₂Y, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val
II	W[S/T][D/E][D/E]VpYXXXXLNBBRM	Ala, Arg, Asn, Asp, F₂Y, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val
III	WAAAApYXXXXXNNBBRM	Ala, Arg, Asn, Asp, F₂Y, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val
IV	AXXXXXpYXXXXXNNBBRM	Ala, Arg, Asn, Asp, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val
V	AXXXXXpYXXXXXEEBBRM	Ala, Arg, Asn, Asp, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val
VI	ANNX⁶X⁵X⁴X³X²X¹AABBRRM	Ala, Arg, Asn, Asp, F₂Y, Gly, Gln, Glu, His, Ile, Leu, Lys, Nle, Phe, Pro, Ser, Thr, Trp, Val, and pY (50% at X¹ position)
VII	Alloc-ASXXXXXpYAABBRM	Ala, Arg (10-fold reduced content), Asn, Asp, F₂Y, Gly, Gln, Glu, His, Ile, Leu, Lys (10-fold reduced content), Nle, Phe, Pro, Ser, Thr, Trp, Val