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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Ther Drug Monit. 2011 Feb;33(1):99–107. doi: 10.1097/FTD.0b013e318203b41e

TABLE 1.

Population model parameter estimates used in the Bayesian forecasting algorithm

Parameter Estimate Units %CV
CLN 7.49 L/h 6.37
CLR 2.55 L/h 75.46
V1 36 L 19.03
V2 3.33 L 52.15
Q .0984 L/h 12.25

CLN , clearance in patients with normal renal function; CLR, clearance in patients with impaired renal function; V1, volume of distribution in the central compartment; V2, volume of distribution in the peripheral compartment, Q, inter-compartmental clearance.