Table 2.
Extract/compound | Parameters | Bacteria strains | |||||
EC | PA | KP | SA | ST | SPB | ||
CH2Cl2/MeOH extract | MIC (mg/ml) | 4 | 3 | 4 | 4 | 6 | 6 |
MBC (mg/ml) | 8 | 7 | 10 | 7 | 12 | 10 | |
MBC/MIC | 2 | 3.5 | 2.5 | 1.75 | 2 | 1.66 | |
Compound 1 | MIC (µg/ml) | 250 | 250 | 200 | 200 | 250 | 250 |
MBC (µg/ml) | 300 | 300 | 300 | 300 | 300 | 300 | |
MBC/MIC | 1.2 | 1.2 | 1.5 | 1.5 | 1.2 | 1.2 | |
Compound 2 | NA | NA | NA | NA | NA | NA | |
Compound 3 | MIC (µg/ml) | 300 | 300 | 250 | 300 | 250 | 250 |
MBC (µg/ml) | >300 | > 300 | > 300 | > 300 | 300 | 300 | |
MBC/MIC | ND | ND | ND | ND | 1.2 | 1.2 | |
Ciprofloxacin | MIC (µg/ml) | 2 | 2 | 2 | 2 | NT | NT |
MBC (µg/ml) | 5 | 5 | 8 | 5 | NT | NT | |
MBC/MIC | 2.5 | 2.5 | 4 | 2.5 | ND | ND | |
Chloramphenicol | MIC (µg/ml) | NT | NT | NT | NT | 2.5 | 2.5 |
MBC (µg/ml) | NT | NT | NT | NT | 20 | 20 | |
MBC/MIC | ND | ND | ND | ND | 8 | 8 |
EC= Escherichia coli; KP=Klebsiella pneumoniae; ST=Salmonella typhi; PA=Pseudomonas aeruginosa; SA= Staphylococcus aureus; SPB=Salmonella paratyphi B; NT = Not tested; NA= Not active; ND= Not determined; MIC= Minimum Inhibitory Concentration; MBC= Minimum Bactericidal Concentration