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. Author manuscript; available in PMC: 2011 Apr 12.
Published in final edited form as: Science. 2005 Nov 24;310(5754):1642–1646. doi: 10.1126/science.1120781

Fig. 2.

Fig. 2

Glucose homeostasis defects in mice lacking LKB1 in liver. (A) Mice of the indicated genotypes were fasted for 18 hours at indicated times after adenoviral Cre injection, and fasting blood glucose was measured. P < 0.01 at all time points. (B) Glucose-tolerance test (GTT) on mice of indicated genotypes 2 weeks after adenoviral Cre injection. (C) Insulin-tolerance test (ITT) on mice of indicated genotypes 2 weeks after adenoviral Cre injection. No significant difference was observed. Data represents the mean + SEM for six mice of each genotype. Average T0 glucose levels for the wild-type mice = 180 mg/dl; average T0 glucose levels for the L/L mice = 355 mg/dl.