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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Angew Chem Int Ed Engl. 2011 Feb 17;50(10):2317–2321. doi: 10.1002/anie.201007494

Figure 1.

Figure 1

CICs enable physical separation of cells and nanoparticles. a) Schematic representation of the composition of the CICs: the primary capsule contains iron oxide and gold nanoparticles, while the secondary-capsule contains islet cells. b) Microscopy image of the CICs (inset: primary microcapsules containing iron oxide and gold nanoparticles). c) Microscopy image of CICs containing beta-TC-6 mouse insulinoma cells present within the shell capsule. d) Viability staining (green =FDA, live cells; red =PI, dead cells) of mouse insulinoma encapsulated in CICs at 48 h after encapsulation demonstrates approximately 90% cell viability.