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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Immunol. 2011 Feb 28;186(7):3836–3840. doi: 10.4049/jimmunol.1003949

FIGURE 3.

FIGURE 3

Attrition of CS252-specific CD8 T cells results in decreased protection against P. berghei sporozoite challenge. Mice were treated as shown in Fig. 1A. Percent of PBL that are CS252-specific CD8 T cells as detected ICS for IFN-γ. Data (mean±S.D.) are from 10 mice per group. Data were analyzed by unpaired two-tailed t-test. Mice were challenged with 1000 Pb sporozoites. Numbers to right of bar graph represents the percent of mice protected against the development of blood stage parasitemia (number protected/number challenged). Data are representative of two experiments. Protection results were analyzed by Fisher’s exact test.