Table 4.
Multiple regression analysis of the age-adjusted effect of tipifarnib following two-cycle timed sequential therapy on duration of CR
Secondary AML |
Adverse cytogenetics |
HR (95% CI) | P |
---|---|---|---|
Yes | Yes | 0.11 (0.03–0.46) | 0.02 |
Yes | No | 0.42 (0.12–1.40) | 0.16 |
No | Yes | 0.69 (0.21–2.24) | 0.53 |
No | No | 2.54 (0.75–8.56) | 0.13 |
NOTE: Adjusted for age <65 versus >65 y (HR, 0.67; P = 0.09).
Abbreviation: 95% CI, 95% confidence interval.