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. Author manuscript; available in PMC: 2011 Apr 12.
Published in final edited form as: Tetrahedron. 2009 Aug 22;65(34):3771–6803. doi: 10.1016/j.tet.2009.05.079

Table 4.2.

Synthesis of trisubstituted cis-β-lactams from disubstituted ketenes.

graphic file with name nihms-194367-t0038.jpg

Entry R1 R2 Ar dr ee (%) Yield (%)
1 −(CH2)5− Ph - 81 84
2 −(CH2)5− 1-Furyl - 92 90
3 −(CH2)5− β-Styryl - 91 82
4 i-Bu Ph Ph 8:1 98 88
6 Et Ph 1-Furyl 9:1 95 97
7 i-Bu Ph β-Styryl 10:1 98 95