Table I.
| Factor | Origin | Primary Tumor | Metastasis |
|---|---|---|---|
| Platelet count | Platelet | ↑ | |
| Platelet microparticles | Platelet | ↑ | |
| P-selectin | Platelet | ↑ | ↑ |
| MAPK p38α | Platelet | No effect | ↑ |
| GP Ibα | Platelet | No effect | ↑ |
| VWF | Platelet, EC | No effect | ↓ |
| GP VI | Platelet | No effect | ↑ |
| GP IIbIIIa | Platelet | ↑ | |
| Fibrinogen | Platelet | ↑ | |
| PAR–1 | Platelet, EC | ↑ | ↑ |
| PAR–2 | EC | ↑ | ↑ |
| PAR–4 | Platelet | ↑ | |
| Thrombin | EC, TC | ↑ | ↑ |
| Chondroitin sulfate glycosaminoglycans | Tumor cells | ↑ | |
| Sialyl Lewis X | Tumor cells | ↑ | |
| TSP-1 | Platelets | ↓ |
EC – Endothelial cells, TC – Tumor cells, ↑- Stimulatory effect, ↓- Inhibitory effect