Schema of CGA use to manage side effects of ADT.
Those persons with no apparent impairments are “fit” and should have no functional dependence, no comorbidities, and no geriatric syndromes. Vulnerable persons may have some dependence in instrumental activities of daily living, non-life threatening comorbidities, and no significant geriatric syndromes other than mild depression or a mild memory disorder. Frail persons can be characterized as those persons aged 85 years and over, those older persons with a dependence in an activity of daily living, three or more significant comorbidities or one comorbidity that is associated with limitation of daily life responsibilities. These definitions are adapted from Balducci and Extermann [188] and Basso et al. [189].