. 2011 Jan 5;300(4):C755–C770. doi: 10.1152/ajpcell.00360.2010

Table 1.

Identification of phosphorylation sites of transport proteins

Protein Name	Gene Symbol	Accession No.	Peptide Sequence	Phosphorylation Site	Relative Location
	Solute carriers
Excitatory amino acid transporter 3	Slc1a1	NP_037164	ALEPTILDNEDS^*DTKK	S496^†	COOH-terminal tail
			SDTIS^*FTQTSQF	S516	COOH-terminal tail
Proton myo-inositol cotransporter	Slc2a13	NP_598295	EAS^*AAGPIICR	S277^†	Loop
Neutral and basic amino acid transport protein rBAT	Slc3a1	NP_058912	DKRDS^*IQMSMK	S10^†	NH₂-terminal tail
			DSIQMS^*MK	S14^†	NH₂-terminal tail
Band 3 anion transport protein	Slc4a1	NP_036783	VLEIPDRDS^*	S18	NH₂-terminal tail
Electrogenic Na-bicarbonate cotransporter 1	Slc4a4	NP_445876	MFSNPDNGS^*PAMTHR	S245	NH₂-terminal tail
			NLTSSS^*LNDISDKPEK	S257	NH₂-terminal tail
			KKGS^*LDSDNDDSDCPYSEK	S1026	COOH-terminal tail
			KGSLDS^*DNDDSDCPYSEK	S1029	COOH-terminal tail
			KKGS^LDS^DNDDSDCPYSEK	S1026, S1029	COOH-terminal tail
Na-glucose cotransporter 2	Slc5a2	NP_072112	S^*GSGSPPPTTEEVAATTR	S619^†	Loop
			SGS^*GSPPPTTEEVAATTR	S621^†	Loop
			SGSGS^*PPPTTEEVAATTR	S623^†	Loop
Na-dependent neutral amino acid transporter B(0)AT3	Slc6a18	NP_058859	NTHLESALKPQES^*R	S612^‡	COOH-terminal tail
Na-dependent neutral amino acid transporter B(0)AT1	Slc6a19	NP_001034811	ALSTAS^*VNGDLKN	S627^†	COOH-terminal tail
Y + L amino acid transporter 1	Slc7a7	NP_112631	DEADGS^*AQGDGAGPAAEQVK	S21	NH₂-terminal tail
Large neutral amino acid transporter small subunit 2	Slc7a8	NP_445894	NHPDRGS^*DTSPEAEASSGGGGVALK	S20^†	NH₂-terminal tail
B(0,+)-type amino acid transporter 1	Slc7a9	NP_446381	EDEKS^*VHSTEPK	S15^†	NH₂-terminal tail
			EDEKS^VHS^TEPK	S15^†, S18^†	NH₂-terminal tail
			EDEKS^VHST^EPK	S15^†, T19^†	NH₂-terminal tail
Na/H exchanger 3	Slc9a3	NP_036786	RGS^*LAFIR	S552	COOH-terminal tail
			HELT^*PNEDEKQDK	T639^†	COOH-terminal tail
			EKDLELS^*EPE	S716	COOH-terminal tail
			VQIPNS^*PSNFR	S791^†	COOH-terminal tail
			VQIPNSPS^*NFR	S793^†	COOH-terminal tail
			DGPEEQLQPAS^*PESTHM	S825^†	COOH-terminal tail
Solute carrier family 12 member 1	Slc12a1	NP_062007	TDTTFHAYDS^*HTNTY	S87^†	NH₂-terminal tail
			YLQTFGHNT^*MDAVPK	T101	NH₂-terminal tail
			S^*LQEIHEQLAK	S126	NH₂-terminal tail
Solute carrier family 12 member 3	Slc12a3	NP_062218	EHYANS^*ALPGEPR	S71	NH₂-terminal tail
			DETGANS^*EKSPGEPVR	S124^†	NH₂-terminal tail
Monocarboxylate transporter 1	Slc16a1	NP_036848	LKS^KES^LQEAGK	S210, S213	Loop
			SKES^*LQEAGK	S213	Loop
			DGKEDETST^*DVDEKPK	T461	COOH-terminal tail
			ETQSPAPLQNSSGDPAEEES^*PV	S492	COOH-terminal tail
Sialin	Slc17a5	NP_001009713	AGNDDEESS^*DSTPLLPSAR	S17^†	NH₂-terminal tail
Solute carrier organic anion transporter family member 1A3	Slc21a4	NP_110464	INS^*SEMEIAEMK	S633^‡	COOH-terminal tail
			INSS^*EMEIAEMK	S634^‡	COOH-terminal tail
Solute carrier family 22 member 2	Slc22a2	NP_113772	ENLPPSQASRPS^*AK	S553^†	COOH-terminal tail
Solute carrier family 22 member 4	Slc22a4	NP_071606	KST^*VSMDREENPK	T537^†	COOH-terminal tail
			STVS^*MDREENPK	S539^†	COOH-terminal tail
Solute carrier family 22 member 5	Slc22a5	NP_062142	QWQIQS^*QTR	S537^†	COOH-terminal tail
			TQKDGGES^*PTVLK	S548^†	COOH-terminal tail
Solute carrier family 22 member 12	Slc22a12	NP_001030115	VTHDIAGGS^*VLK	S546^†	COOH-terminal tail
Solute carrier family 23 member 1	Slc23a1	NP_059011	QHECPDS^*AGTSTR	S18^†	NH₂-terminal tail
			QHECPDS^AGTS^TR	S18^†, S22^†	NH₂-terminal tail
			DAPDNTET^*GSVCTKV	T597^†	COOH-terminal tail
			TENQPAVLEDAPDNTETGS^*VCTK	S599	COOH-terminal tail
Solute carrier family 23 member 2	Slc23a2	NP_059012	ETLDSTGS^*LDPQR	S25	NH₂-terminal tail
Sulfate anion transporter 1	Slc26a1	NP_071623	GTEVGVS^*NR	S586	COOH-terminal tail
Na-dependent phosphate transport protein 2A	Slc34a1	NP_037162	AVS^*PLPVR	S14^†	NH₂-terminal tail
			EELPPAT^PS^PR	T621^†, S623^†	COOH-terminal tail
			VFLEELPPATPS^*PR	S623^†	COOH-terminal tail
Na-dependent phosphate transport protein 2C	Slc34a3	NP_647554	GETPQGS^*SEECDLSGSCTER	S285^†	Loop
			GETPQGSS^*EECDLSGSCTER	S286^†	Loop
Large neutral amino acid transporter small subunit 4	Slc43a2	NP_001099282	RLS^*VGSSMR	S274	Loop
Solute carrier organic anion transporter family member 1A1	Slco1a1	NP_058807	ESEHTDVHGS^*PQVENDGELK	S657^†	COOH-terminal tail
Solute carrier organic anion transporter family member 4C1	Slco4c1	NP_001002024	GVENPAFVPS^*SPDTPRR	S15^†	NH₂-terminal tail
			GVENPAFVPSS^*PDTPR	S16^†	NH₂-terminal tail
			S^*ASPSQVEVSAVASR	S24^†	NH₂-terminal tail
			S^ASPS^QVEVSAVASR	S24^†, S28^†	NH₂-terminal tail
Predicted: similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12	LOC688389	XP_001066729	DEQDKNLCS^*E	S553^‡	COOH-terminal tail
	ATP binding cassettes
ATP-binding cassette, subfamily B (MDR/TAP), member 1A	Abcb1a	NP_596892	DSGSS^*LIR	S653	Loop
ATP-binding cassette subfamily G member 2	Abcg2	NP_852046	DHVLVPMS^*QR	S13^‡	NH₂-terminal tail
Multidrug resistance-associated protein 4	Abcc4	NP_596902	ENEEAEPSPVPGT^*PTLR	T646	Loop
Similar to ATP-binding cassette, subfamily G (white), member 3	LOC360997	NP_001032282	RHS^*DLPETNTS	S18^‡	NH₂-terminal tail
	ATPase
V-type proton ATPase 116-kDa subunit a isoform 4	Atp6v0a4	NP_001100061	SQLQS^*FTIHE	S645^†	Loop
V-type proton ATPase subunit H	Atp6v1 h	NP_001013951	QEMLQTEGS^*QCAK	S71^†	Non-transmembrane protein
Predicted: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	Atp8a1	XP_001070245	TDDVSEKTS^*LADQEEVR	S29	NH₂-terminal tail
Probable phospholipid-transporting ATPase IH	Atp11a	NP_001100794	DS^*FSGLSTDMH	S747	Loop
Predicted: similar to probable cation-transporting ATPase 13A3 (ATPase family homolog upregulated in senescence cells 1)	LOC292449	XP_001067586	HDS^*LEDLQVTR	S744^‡	Loop

Phosphorylated amino acid.

^†

Novel phosphorylation site.

^‡

Protein not in www.phosphosite.org database.