Table 4.
Identification of phosphorylation sites of PDZ domain proteins
| Protein Name | Gene Symbol | Accession No. | Peptide Sequence | Phosphorylation Site |
|---|---|---|---|---|
| Whirlin | Dfnb31 | NP_851602 | FDHLVLRREIES* | S501† |
| LIM domain only protein 7 | Lmo7 | NP_001001515 | EVSRS*PDQFSDMR | S1061† |
| SRS*TTELNDPLIEK | S1476 | |||
| SHS*PSMSQSGSQLR | S1639 | |||
| p55 protein | LOC652956 | NP_001032748 | TNGS*VDLGEEEEAAR | S57† |
| Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | Mpp5 | NP_001101504 | KQELDLNSS*MR | S84† |
| Na/H exchange regulatory cofactor NHE-RF3 | Pdzk1 | NP_113900 | DQS*PREPALNEK | S108† |
| EGNS*FGFSLK | S144† | |||
| S*NGYGFYLR | S250† | |||
| SQELPNGS*VK | S348† | |||
| TLSAAS*HSSSNSE | S512 | |||
| TLSAAS*HSS*SNS*EDTVM | S512, S515†, S518 | |||
| TLSAAS*HSSS*NS*EDTVM | S512, S516, S518 | |||
| TLSAASHS*SSNS*EDTVM | S514, S518 | |||
| TLSAASHS*S*SNS*EDTVM | S514, S515†, S518 | |||
| TLSAASHSS*S*NSEDTVM | S515†, S516 | |||
| TLSAASHSS*SNS*EDTVM | S515†, S518 | |||
| TLSAASHSSS*NS*EDTVM | S516, S518 | |||
| Rap guanine nucleotide exchange factor 2 | Rapgef2 | NP_001101154 | SETS*PVAPR | S820 |
| Signal-induced proliferation-associated 1-like protein 1 | Sipa1l1 | NP_647546 | LIDLES*PTPESQK | S1567 |
| Na/H exchange regulatory cofactor NHE-RF1 | Slc9a3r1 | NP_067605 | NGYGFNLHS*DK | S167† |
| AS*ESPRPALAR | S275 | |||
| LVEPASES*PRPALAR | S277 | |||
| S*ASSDTSEELNAQ | S285 | |||
| S*AS*SDTSEELNAQDSPK | S285, S287 | |||
| S*ASSDT*SEELNAQDSPK | S285, T290 | |||
| S*ASSDTS*EELNAQDSPK | S285, S291 | |||
| SAS*SDTSEELNAQDSPKR | S287 | |||
| SAS*S*DTSEELNAQDSPK | S287, S288 | |||
| SAS*SDT*SEELNAQDSPK | S287, T290 | |||
| SAS*SDTS*EELNAQDSPK | S287, S291 | |||
| SAS*SDTSEELNAQDS*PKR | S287, S299 | |||
| SAS*SDTS*EELNAQDS*PK | S287, S291, S299 | |||
| SASS*DTSEELNAQDSPK | S288 | |||
| SASS*DT*SEELNAQDSPK | S288, T290 | |||
| SASS*DTS*EELNAQDSPK | S288, S291 | |||
| SS*DTSEELNAQDS*PKR | S288, S299 | |||
| SASS*DTS*EELNAQDS*PKR | S288, S291, S299 | |||
| SASSDT*SEELNAQDSPK | T290 | |||
| SASSDT*S*EELNAQDSPK | T290, S291 | |||
| SSDT*SEELNAQDS*PKR | T290, S299 | |||
| SASSDT*S*EELNAQDS*PKR | T290, S291, S299 | |||
| SSDTS*EELNAQDSPK | S291 | |||
| SASSDTS*EELNAQDS*PKR | S291, S299 | |||
| SASSDTSEELNAQDS*PK | S299 | |||
| Na/H exchange regulatory cofactor NHE-RF2 | Slc9a3r2 | NP_446263 | SDLPGS*EKDNEDGSAWK | S280† |
| Tight junction protein ZO-2 | Tjp2 | NP_446225 | RQQYS*DQEYHSSTEK | S404 |
| DGS*PPPAFKPEPPK | S966 | |||
| Usher syndrome 1C | Ush1c | NP_997686 | EMEQIS*EEEEK | S364† |
| Myosin 18a | LOC360570 | NP_001165608 | HNYLS*DS*DTEAK | S2041, S2043 |
| HNYLSDS*DTEAK | S2043 | |||
| Predicted: InaD-like (Drosophila) isoform 2 | Inadl | XP_001055452 | KTS*LSASPFEQPSSR | S455† |
| DDEAS*VDEPR | S647 |
*
Phosphorylated amino acid.
†
Novel phosphorylation site.
‡
Protein not in www.phosphosite.org database.