Table 3.
Young | Aged | Aged + Fish Oil | |
LV structure | |||
HW/BW (mg/g) | 4.0 ± 0.30 | 3.1 ± 0.07 | 3.2 ± 0.16 |
LVEDD (cm)* | 0.756 ± 0.010† | 0.903 ± 0.035 | 0.905 ± 0.017 |
LVESD (cm)* | 0.378 ± 0.011† | 0.492 ± 0.033 | 0.512 ± 0.021 |
PWTed (cm)* | 0.158 ± 0.003† | 0.209 ± 0.005‡ | 0.192 ± 0.004 |
AWTed (cm) | 0.182 ± 0.006 | 0.203 ± 0.007 | 0.198 ± 0.006 |
RWT | 0.418 ± 0.009 | 0.469 ± 0.030 | 0.426 ± 0.010 |
LV mass | 0.589 ± 0.038† | 1.448 ± 0.135 | 1.327 ± 0.061 |
LV systolic function | |||
FS (%)* | 50 ± 1‡ | 46 ± 2 | 44 ± 2 |
VCFc (circ/s) | 0.987 ± 0.023 | 0.994 ± 0.034 | 0.960 ± 0.037 |
HR (beats/min)* | 348 ± 7† | 291 ± 4 | 304 ± 5 |
LV diastolic function | |||
Emax (cm/s) | 72 ± 2 | 77 ± 2 | 74 ± 2 |
Edec time (s) | 0.050 ± 0.002 | 0.052 ± 0.002 | 0.050 ± 0.002 |
Edec slope (cm/s) | 14 ± 1 | 14 ± 1 | 15 ± 1 |
e’ (cm/s)* | 5.0 ± 0.3§ | 3.6 ± 0.3 | 4.1 ± 0.3 |
E/e’* | 14.9 ± 1.0§ | 21.6 ± 1.2 | 18.6 ± 1.0 |
Notes: AWTed = anterior wall thickness at end diastole; e’ = early mitral annular velocity; E/e’ = transmitral early filling/early mitral annular velocity; Edec = deceleration time of early filling; Emax = transmitral early filling velocity; FS = fractional shortening; HR = heart rate; HW/BW = heart weight/body weight; LV = left ventricular; LVEDD = left ventricular end-diastolic dimension; LVESD = left ventricular end-systolic dimension; PWTed = posterior wall thickness at end diastole; RWT = relative wall thickness; VCFc = mean velocity of circumferential fiber shortening corrected for heart rate.
p < .05, main effect of group.
p < .01 vs aged, aged + fish oil.
p < .05 vs aged + fish oil.
p < .05 vs aged.