Skip to main content
. Author manuscript; available in PMC: 2011 Apr 12.
Published in final edited form as: J Immunol. 2009 Aug 19;183(6):4103–4108. doi: 10.4049/jimmunol.0900852

FIGURE 2.

FIGURE 2

T. cruzi-specific CD4+ T cells in chronically infected subjects are primarily recently recruited T cells. The CD4 IFN-γ double-positive compartment was analyzed for the expression of CD27, CD28, and CD57 by flow cytometry (A). Bars represent the mean frequencies of CD4+ IFN-γ+ T cells expressing CD27 and CD28 in chronically T. cruzi-infected subjects; error bars indicate SD. Number of subjects studied in each patient group: G0 = 7, G1 = 7, G2 = 2, and G3 = 4. B, CD57 expression on CD4+IFN-γ+ T cells in the different clinical stages of the disease. Median values are represented by horizontal lines. C and D, Correlation between the expression of CD27, CD28, and CD57 on T. cruzi-specific IFN-γ-producing CD4+ T cells was evaluated by the Spearman correlation test.