Table 1.
Normal Zone |
Ischemic Zone |
|||||||
---|---|---|---|---|---|---|---|---|
Endocardium |
Epicardium |
Endocardium |
Epicardium |
|||||
CAO5′ | CAO50′ | CAO5′ | CAO50′ | CAO5′ | CAO50′ | CAO5′ | CAO50′ | |
LacZ (n = 5) | 1.11 ± 0.10 | 1.20 ± 0.10 | 1.02 ± 0.11 | 1.15 ± 0.13 | 0.04 ± 0.02 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.03 ± 0.02 |
H11 (n = 4) | 1.19 ± 0.11 | 1.13 ± 0.10 | 0.84 ± 0.07 | 0.77 ± 0.04 | 0.05 ± 0.03 | 0.03 ± 0.02 | 0.08 ± 0.03 | 0.01 ± 0.03 |
Values (in ml·min−1·g−1) are mean ± SE absolute flow in both subendocardium and subepicardium of the remote and ischemic areas after the onset (5 min CAO) and before the end (50 min CAO) of coronary artery occlusion. H11, H11 kinase/Hsp22. No significant difference between groups was detected.