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Leptin lowers serum cholesterol and triglycerides in hypoxic wild-type (WT) animals. Hypoxia-induced elevations in fasting serum total cholesterol (A) and total triglycerides (B) were lowered with exogenous leptin treatment, whereas serum free fatty acids (C) tended toward a decrease with leptin treatment. Values are means ± SE, n = 5/group. *P < 0.05 vs. no exogenous leptin.
