Table 1.
Description of the sample by case–control status
| Cases (n = 667) | Controls (n = 662) | Pa | |
|---|---|---|---|
| Demographic and lifestyle factors | |||
| Age | 61.1 (9.44) | 62.1 (10.71) | 0.0526b |
| Race | 0.0096 | ||
| White | 606 (90.85) | 625 (94.55) | |
| Other | 61 (9.15) | 36 (5.45) | |
| Education | 0.0003 | ||
| 12 years or less | 237 (35.53) | 174 (26.32) | |
| Greater than 12 years | 430 (64.47) | 487 (73.68) | |
| Body mass index (kg/m2) | 32.6 (8.54) | 27.1 (6.07) | 1.78 × 10−38 |
| Smoking status | 0.0187 | ||
| Never smoker | 364 (54.57) | 311 (46.98) | |
| Former smoker | 251 (37.63) | 285 (43.05) | |
| Current smoker | 52 (7.80) | 66 (9.97) | |
| Ever drank alcohol regularly | 307 (46.23) | 400 (60.51) | 3.79 × 10−7 |
| Reproductive factors | |||
| Number of live births | 1.8 (1.36) | 2.1 (1.32) | 4.42 × 10−6 |
| Ever gravid | 525 (78.71) | 586 (88.52) | 2.76 × 10−6 |
| Age at first pregnancy | 23.5 (4.71) | 24.7 (4.96) | 3.13 × 10−5 |
| Menopausal status | 0.031 | ||
| Premenopausal | 91 (13.66) | 119(17.98) | |
| Postmenopausal | 575 (86.34) | 543 (82.02) | |
| Oral contraceptive use (ever) | 374 (56.33) | 440 (66.67) | 0.0001 |
| Menopausal hormone use (ever) | 198 (30.23) | 239 (37.52) | 0.0056 |
| Menarche age | 0.047 | ||
| < 12 year | 186 (28.10) | 153 (23.32) | |
| ≥12 year | 476 (71.90) | 503 (76.68) | |
| Medical history | |||
| Family history (yes/no 1st degree relative with endometrial cancer) | 46 (6.90) | 27 (4.08) | 0.024 |
| MD diagnosis of hypertension (ever) | 378 (56.67) | 257 (38.82) | 1.43 × 10−10 |
| MD diagnosis of diabetes (ever) | 136 (20.39) | 77 (11.63) | 2.70 × 10−5 |
Table values are mean (SD) for continuous variables and n (column %) for categorical variables
a
p-value is for t-test (continuous variables) or χ2 test (categorical variables)
b
Matched