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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Wound Repair Regen. 2011 Mar–Apr;19(2):205–213. doi: 10.1111/j.1524-475X.2010.00656.x

Figure 2.

Figure 2

Serial IHC sections show the localization of hypoxia, HIF-1 α, and SDF-1 in the leading zone: IHC of hypoxia (pimonidazole-1 staining, upper panel), HIF-1α (middle panel), and SDF-1 (lower panel) were carried out 72 hours after burn. The Leading Zone (in red) showed positive brown staining for all 3 markers. The Adjacent Zone (in blue) and normal skin (in yellow) did not stain positively for the markers. Serial sections from the same tissue block show the co-localized regions of the 3 stains.