Table 4.
Lack of APOE genotype effect on baseline lipids, insulin, and glucose
|
APOE Genotype |
||||
|---|---|---|---|---|
| Variable | ε2/ε3 | ε3/ε3 | ε4/ε3 | APOE Genotype Effect, P Value |
| n | 53 | 59 | 45 | |
| TC, mg/dl | 194.8 ± 38.2 | 207.2 ± 37.8 | 198.0 ± 37.4 | 0.19 |
| TG, mg/dl | 142.2 ± 103.3 | 128.8 ± 81.7 | 123.7 ± 81.1 | 0.53 |
| LDL-C, mg/dl | 118.3 ± 31.0 | 133.9 ± 32.7 | 129.9 ± 36.4 | 0.07 |
| HDL-C, mg/dl | 48.5 ± 13.0 | 48.5 ± 14.0 | 44.8 ± 11.3 | 0.11 |
| HDL2-C, mg/dl | 12.2 ± 7.5 | 10.6 ± 7.8 | 10.2 ± 7.1 | 0.28 |
| HDL3-C, mg/dl | 36.0 ± 6.7 | 36.3 ± 6.0 | 35.0 ± 7.5 | 0.58 |
| Glucose, mg/dl | 81.4 ± 7.3 | 81.6 ± 8.2 | 80.6 ± 6.5 | 0.80 |
| Insulin, μU/ml | 6.1 ± 3.1 | 5.8 ± 3.1 | 7.9 ± 11.9 | 0.87 |
| HOMA | 1.23 ± 0.71 | 1.22 ± 0.69 | 1.33 ± 0.99 | 0.68 |
Data are means ± SD; n = no. of subjects with each genotype. HOMA, homeostatic model assessment of insulin resistance.