Table 3. Repeated measures analysis of covariancea modeling the association between early weight gainb and percentage change in body mass index (BMI) after 12 and 18 months of DMPA use.
Factor | P-value | Mean (SD) |
---|---|---|
Early Weight Gain | <0.001 | No vs. Yes |
3.7% (0.9%) vs. 14.7% (1.9%) | ||
Visit Month | 0.03 | 12 vs. 18 |
7.3% (1.2%) vs. 11.0% (1.5%) |
Eligible co-variables included age, gynecologic age, race, ethnicity, BMI, menstrual regularity, duration of menses, menstrual cycle length, sexual activity, previous pregnancy, physical activity, randomization to estradiol or placebo, and time by group interaction.
Early weight gain defined as: No = gained ≤ 5% of baseline weight at 6 months of DMPA use; Yes = gained > 5% of baseline weight at 6 months of DMPA use.