Table 4.
Results of PCR on RDT and presence of antigen test lines for OptiMAL and SDFK60 tested with a panel of clinical samples
| OptiMAL | SDFK60 | |||||
|---|---|---|---|---|---|---|
| Correct DNA detection by PCR on RDT | Correct antigen detection by RDT | Correct DNA detection by PCR on RDT | Correct antigen detection by RDT | |||
| PCR on whole blood | Parasite density | Nrs | Nrs | Nrs | Nrs | Nrs |
| P. falciparum | only gametocytes | 10 | 10 | 6 | 9 | 9 |
| 1-100 | 10 | 10 | 4 | 10 | 10 | |
| 101-500 | 15 | 15 | 14 | 15 | 15 | |
| 501-1000 | 5 | 5 | 5 | 5 | 5 | |
| >1000 | 20 | 20 | 20 | 20 | 20 | |
| P. vivax | only gametocytes | 1 | 1 | 0 | 1 | 0 |
| 1 to >1000 | 10 | 10 | 10 | 10 | 9 | |
| P. ovale | 1 to >1000 | 10 | 10 | 2 | 10 | 4 |
| P. malariae | 1 to >1000 | 10 | 10 | 6 | 10 | 6 |
| Total single infections | 0 to >1000 | 91 | 91 | 67 | 90 | 78 |
| Mixed infections | 1 to >1000 | 5 | 4 | 3# | 2 | 1# |
| After start of treatment | 0 | 15 | 11 | 1 | 7 | 15 |
| Negative | 0 | 10 | 10 | 10 | 10 | 10 |
| Total | 121 | 116 | 81 | 109 | 104 | |
PCR on whole blood was the reference method.
# numbers of RDT samples with two positive test lines