Skip to main content
. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Apr 15;21(8):2192–2197. doi: 10.1016/j.bmcl.2011.03.015

Table 3.

Inhibition activities for caspase-3 in HeLa cells.

graphic file with name nihms-285939-t0006.jpg
Compd. n X R EC50 (μM)a
9 1 CH graphic file with name nihms-285939-t0007.jpg 2.00±0.44
10 1 CH graphic file with name nihms-285939-t0008.jpg 2.15±0.45
WC-II-89 b 2 CH graphic file with name nihms-285939-t0009.jpg 4.50±1.10
14 2 CH graphic file with name nihms-285939-t0010.jpg 1.69±0.18
15 2 CH graphic file with name nihms-285939-t0011.jpg 1.30±0.25
12 1 N graphic file with name nihms-285939-t0012.jpg 0.38±0.07
16 2 N graphic file with name nihms-285939-t0013.jpg 0.39±0.09
37 1 CH graphic file with name nihms-285939-t0014.jpg 0.80±0.06
38 1 N graphic file with name nihms-285939-t0015.jpg 0.42±0.10
39 2 CH graphic file with name nihms-285939-t0016.jpg 0.93±0.21
40 2 N graphic file with name nihms-285939-t0017.jpg 0.35±0.04
Compd. n R EC50 (μM)a
48 1 graphic file with name nihms-285939-t0018.jpg 1.39±0.40
49 2 graphic file with name nihms-285939-t0019.jpg 2.50±0.80
50 1 graphic file with name nihms-285939-t0020.jpg 1.06±0.20
51 2 graphic file with name nihms-285939-t0021.jpg 0.68±0.39
a

IC50 values are the mean ± SD of at least three independent assays

b

reference 14.