Table 1. Differentially expressed microRNAs in APC and CAC tumors.

	APC control vs APC tumor			CC control vs CAC tumor
miRNA	Ave rank order diff.	p-value	miRNA	Ave rank order diff.	p-value
miR-215	−75	0.0014	miR-215	−48	0.0042
miR-137	−57	0.0206	miR-133a	38	0.0014
miR-708	69	0.0022	miR-467d	40	0.0147
miR-31	110	0.0021	miR-218	42	0.0018
miR-135b	126	<0.0001	miR-708	62	0.0014
			miR-31	98	<0.0001
			miR-135b	101	0.0014

Rank order differences were determined by subtracting the average rank order of individual microRNAs in each group of tumor samples from the rank order in the corresponding control (e.g. APC control rank – APC tumor rank = rank order diff.). Signficance (p-value) was assessed using the t-test (assuming unequal variance) to compare rank orders of individual microRNAs in tumors and controls.