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. 2011 Apr 12;6(4):e18632. doi: 10.1371/journal.pone.0018632

Figure 1. Bacillary load and extent of Th1 response in the lungs of Wistar rats infected by the endotracheal route with Mycobacterium tuberculosis.

Figure 1

A, Number of Mtb colony-forming units in the lungs of rats infected with HN878 or H37Rv. The difference in Mtb load between the two strains at day 14 and 60 was significant (P<0.005). Values are means ± SD. B, Interferon gamma (IFN-γ) production by lung cells from Mtb infected rats following ex vivo stimulation with ESAT6+CFP10 and PPD antigens. Values are means ± SE. C, IFN-γ and monocyte chemotactic protein-1 (MCP-1) levels in the BAL fluid of rats infected with HN878 and H37Rv. Values are means ± SEs. (*P<0.05, ** P<0.01, *** P<0.001).