Skip to main content
. 2011 Jan 27;105(4):1506–1515. doi: 10.1152/jn.00950.2010

Fig. 5.

Fig. 5.

Evoked excitatory neurotransmission in Cc2d1a KO neurons. A: top: average of excitatory postsynaptic currents (EPSCs) evoked at 14 DIV cultures of control or Cc2d1a KO neurons. AP, action potential. Bottom: all the 20-Hz stimulation peaks were significantly different between the 2 groups. Inset: representative traces for the initial peaks of control and Cc2d1a KO groups. At the end of the 20-Hz stimulation paradigm, switching to 1-Hz stimulation enabled rapid recovery of both control and Cc2d1a KO synaptic response to their initial values (n = 11 for control and n = 10 for KO cells). B and C: representative traces (B) and mean charge movement values integrated during the first 10 s of 20-s hypertonic stimulation (with the addition of 0.5 M sucrose) of excitatory synapses (C) in control and Cc2d1a KO neurons. These experiments did not reveal a significant difference between the 2 groups (n = 6 for both, P > 0.05).