Table 2.
Molecular and Gd(III) ionic relaxivity of Zn-Pz-nGd(III) (n=1, 4, 8) complexes in water at 37 °C, 60 MHz.
Compounds | MW (g/mol) | Gd(III) ionic r1(mM−1 s−1) | No. of Gd(III) | Molecular r1(mM−1 s−1) |
---|---|---|---|---|
Gd595 | 595.7 | 3.21 | 1 | 3.21 |
Zn-Pz-1Gd(III) | 1985.6 | 4.2* | 1 | 4.2* |
Zn- Pz-4Gd(III) | 3893.9 | 10.5 | 4 | 42 |
Zn- Pz-8Gd(III) | 6496.9 | 12.8 | 8 | 102.4 |
measured in DMSO/Water, v/v=1:5