Table 1.

Baseline Characteristics of Kawasaki Disease Trial Subjects by IVIG Retreatment Status. Mean±SD (median) or % unless otherwise specified.

Variable	N	IVIG Retreated	N	Not IVIG- Retreated	p-value*
Age, years	27	3.7±2.5 (3.3)	171	3.2±2.2 (2.8)	.30
Age ≤ 1 year	27	7%	171	18%	.26
Age < 6 months	27	4%	171	5%	1.00
Male	27	82%	171	60%	.033
Hispanic	25	20%	165	18%	.78
Race	27		171		.51
White		48%	102	60%
Black		26%	30	18%
Asian		19%	22	13%
Other/Mixed/Unknown		7%	17	10%
Fever Days prior to Diagnosis	27	6.3±1.6 (6.0)	171	6.6±1.5 (6.0)	.34*
Fever Days ≤ 4	27	7%	171	6%	.67
Assigned to Steroids	27	44%	171	52%	.54
Received Steroids	27	41%	171	52%	.41
Baseline Echo Z-Scores
Proximal RCA	24	1.2±1.3 (0.9)	166	1.2±1.4 (1.0)	.96*
Proximal LAD	26	1.3±1.7 (1.1)	167	1.1±1.5 (1.0)	.58*
Max Z (pRCA, pLAD)	26	1.8±1.7 (1.5)	169	1.6±1.5 (1.4)	.69*
Left Main	26	1.1±1.0 (1.1)	168	0.9±1.1 (0.7)	.29*
Baseline Laboratory Values
C-Reactive Protein, mg/dL	22	12.9±8.3 (14.3)	116	9.2±8.0 (6.8)	.06
C-Reactive Protein ≥ 10 mg/dL	22	59%	116	33%	.03
ESR, mm/hr	25	63±34	162	68±32	.48*
White blood cell count, 103/mm3	27	12.9±5.0	171	14.0±5.5	.30
% Neutrophils	26	60±25 (66)	171	55±21 (59)	.13
Neutrophils ≥ 80%	26	23%	171	8%	.03
Hematocrit, %	27	31±5	171	32±3	.18*
Hemoglobin, g/dL	27	10.6±1.5	171	11.0±2.2	.10*
Platelets × 104/mm3	27	34.1±9.0 (32.9)	171	40.2±14.7 (39.4)	.005*
Plaletets ≤ 30 × 104/mm3	27	33%	171	23%	.34
Albumin, g/dL	27	2.9±0.6	155	3.4±0.6	.0003*
IgG, median	25	714	138	687	.54
IgA, median	25	92	133	82	.98
IgM, median	25	97	132	110	.65
ALT, IU/L, median	20	70.0	144	28.5	.06
AST, IU/L, median	20	39.0	128	34.0	.40
AST ≥ 100 IU/L	20	10%	128	10%	1.0
Sodium, mmol/L	19	135±2	124	136±3	.28
Sodium < 133 mmol/L	19	16%	124	13%	.72
Total bilirubin, mg/dL, median	17	0.9	100	0.3	.12
Total bilirubin ≥ 0.9 mg/dL	17	53%	100	21%	.01

^*p-value for proportions from exact test; p-value for continuous variables from Wilcoxon rank sum test except where noted with an asterisk to indicate t-test N represents the total available sample size for the variable in each group.

IVIG= Intravenous immunoglobulin

RCA= Right coronary artery

LAD= Left anterior descending coronary artery

pRCA= Proximal RCA

pLAD= Proximal LAD

ESR= Erythrocyte sedimentation rate

IgG=Immunoglobulin G

IgA=Immunoglobulin A

IgM=Immunoglobulin M

ALT=Alanine aminotransferase

AST=Aspartate aminotransferase