Table 4.
Distribution of Kobayashi, Egami, and Sano Risk Scores by IVIG Retreatment Status in Subjects who did not Receive Steroid Therapy
| All | IVIG-Retreated | Not IVIG- Retreated |
p-value* | |
|---|---|---|---|---|
| N | 62 | 9 | 53 | |
| Kobayashi Score† | 1.7±1.6 | 2.4±1.9 | 1.5±1.6 | 0.14 |
| Median score (IQR) | 1.0 (0, 3.0) | 2.0 (1.0, 4.0) | 1.0 (0, 3.0) | |
| Kobayashi Score | 0.40, 0.12 | |||
| 0 | 29% | 11% (1) | 32% (17) | |
| 1 | 31% | 33% (3) | 30% (16) | |
| 2 | 11% | 11% (1) | 11% (6) | |
| 3 | 13% | 11% (1) | 13% (7) | |
| 4 | 8% | 11% (1) | 8% (4) | |
| 5 | 7% | 22% (2) | 4% (2) | |
| 6 | 2% | 0.0% | 2% (1) | |
| Low Risk (0–3) | 84% | 67% | 87% (specificity) | |
| High Risk (≥ 4) | 16% | 33% (sensitivity) | 13% | |
| N | 78 | 12 | 66 | |
| Egami Score† | 1.3±1.3 | 2.1±1.2 | 1.1±1.3 | 0.01 |
| Median score (IQR) | 1.0 (0, 2.0) | 2.0 (1.5, 3.0) | 1.0 (0, 1.0) | |
| Egami Score | 0.01, 0.02 | |||
| 0 | 35% | 17% (2) | 38% (25) | |
| 1 | 33% | 8% (1) | 38% (25) | |
| 2 | 13% | 33% (4) | 9% (6) | |
| 3 | 13% | 33% (4) | 9% (16) | |
| 4 | 4% | 8% (1) | 3% (2) | |
| 5 | 3% | 0% | 3% (2) | |
| Low Risk (0–2) | 81% | 58% | 85% (specificity) | |
| High Risk (≥ 3) | 19% | 42% (sensitivity) | 15% | |
| N | 56 | 10 | 46 | |
| Sano Score† | 0.9±0.8 | 1.5±0.7 | 0.8±0.8 | 0.03 |
| Median score (IQR) | 1.0 (0, 1.0) | 1.0 (1.0, 2.0) | 1.0 (0, 1.0) | |
| Sano Score | 0.03, 0.01 | |||
| 0 | 32% | 0% | 39% (18) | |
| 1 | 48% | 60% (6) | 46% (21) | |
| 2 | 16% | 30% (4) | 13% (6) | |
| 3 | 4% | 10% (1) | 2% (1) | |
| Low Risk (0–1) | 80% | 60% | 85% (specificity) | |
| High Risk (2–3) | 20% | 40% (sensitivity) | 15% | |
Wilcoxon rank sum test p-value for continuous score; Exact test and Mantel-Haenszel test for linear trend p-value for categorical distribution
Mean±standard deviation
IQR = Interquartile range