Table 1. Allele and genotype frequencies for two SNPs in the ADH1B proximal promoter region.
Allele and genotype frequencies in different populations for the two SNPs that were associated with alcoholism were obtained from HapMap (release 27, Phase II and III; hapmap.ncbi.nlm.nih.gov). Populations are Utah residents with ancestry from northern and western Europe (CEU), Han Chinese in Beijing, China (CHB), Japanese in Tokyo, Japan (JPT), Yoruba in Ibadan, Nigeria (YRI).
| rs1229982 | rs1159918 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Allele | Genotype | Allele | Genotype | |||||||
| HapMap Population | A | C | A/A | C/A | C/C | T | G | T/T | T/G | G/G |
| CEU | 0.2 | 0.8 | 0.0 | 0.3 | 0.7 | 0.3 | 0.7 | 0.1 | 0.4 | 0.5 |
| CHB | 0.0 | 1.0 | 0.0 | 0.1 | 0.9 | 0.2 | 0.8 | 0.0 | 0.3 | 0.6 |
| JPT | 0.0 | 1.0 | 0.0 | 0.1 | 0.9 | 0.2 | 0.8 | 0.0 | 0.3 | 0.7 |
| YRI | 0.6 | 0.4 | 0.3 | 0.5 | 0.2 | 0.9 | 0.1 | 0.8 | 0.2 | 0.0 |