Table 2.
Sorting signals that may be involved in clathrin-mediated endocytosis of adherens and tight junction proteinsa
| Protein (PubMed accession number) | Sequence position | YXXØ- type sorting signals | EXXXLL- type sorting signals |
|---|---|---|---|
| E-cadherin (NP-004351) | 737-743 | VVKEPLL | |
| 827-830 | YDSL | ||
| 859-862 | YDYL | ||
| β-catenin (NP-001895) | 155-160 | ELTKLL | |
| 604-607 | YSPI | ||
| 716-719 | YRSF | ||
| p120 catenin (AAC39808) | 190-193 | YDDL | |
| 354-359 | ALVRLL | ||
| 731-734 | YKEL | ||
| Occludin (AAH29886) | 172-175 | YLSV | |
| 481-484 | YNRL | ||
| ZO-1 (Q07157) | 252-257 | ERATLL | |
| 495-498 | YRRI | ||
| 1512-1515 | YNRF | ||
| Claudin-4 (AAH00671) | 92-97 | ALGVLL | |
| 165-168 | YVGW |
a
Key residues are indicated in bold type.