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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Nutr Biochem. 2010 Dec 15;22(8):777–783. doi: 10.1016/j.jnutbio.2010.07.002

Figure 3.

Figure 3

Effect of stigmasterol on the expression of LXR (A) and SREBP1 (B), SREBP2 (C) and selected target genes in mouse peritoneal macrophages. Macrophages were elicited and cultured as in Figure 1. On day 2, the medium was removed and replaced with Medium C (Control) or Medium C supplemented with TO901317 (1 μM), sitosterol (10 μg/ml), stigmasterol (10 μg/ml), or 25-OH-C (1 μg/ml) for 24 h. Total RNA was isolated and processed for quantitative RT-PCR. Asterisks denote significant differences from control treated cells (p < 0.01).