Table 1.
Characteristics of innate T helper type 2 cytokine-producing cells as examined by surface phenotypes
| Cells | ||||
|---|---|---|---|---|
| Markers | NH cell | Nuocyte | MPPtype2 | Ih2 cell |
| c-Kit | + | ± | + | ± |
| CD45 | + | + | + | + |
| IL-7Rα | + | lo | −/lo | ? |
| Sca-1 | + | + | + | − |
| Thy-1 | + | + | ? | + |
| CD34 | − | − | −/lo | ? |
| CD25 | + | −1 | ? | +1 |
| CD44 | + | + | ? | + |
| CD69 | + | ? | − | +1 |
| CD62L | − | ? | −/lo | ? |
| FcεRI | − | − | − | ? |
| T1/ST2 | + | ± | −/lo | ? |
| MHC class II | − | + | ?2 | ? |
1
Based on microarray analysis.
2
GFP− cells expressed MHC class II after cultivation with a combination of interleukin-3 and stem cell factor.
NH, natural helper; MPP, multipotent progenitor; Ih2, innate helper type 2; IL-7R, interleukin-7 receptor.