Table 1.
Main features of the 10 human TLR molecules.
| TLR | Residues | LRRsa | N-linked glycosylation sitesb | Accession code |
|---|---|---|---|---|
| 1 | 786 | 19 | 4 (7) | Q15399 |
| 2 | 784 | 19 | 3 (4) | O60603 |
| 3 | 904 | 23 | 11 (15) | O15455 |
| 4 | 839 | 21 | 5 (10) | O00206 |
| 5 | 858 | 20 | (7) | O60602 |
| 6 | 796 | 19 | 8 (9) | Q9Y2C9 |
| 7 | 1049 | 25 | (14) | Q9NYK1 |
| 8 | 1041 | 25 | (18) | Q9NR97 |
| 9 | 1032 | 25 | (18) | Q9NR96 |
| 10 | 811 | 19 | (8) | Q9BXR5 |
a
The number of LRRs in the extracellular domain do not include the LRR-NT or LRR-CT motifs.
b
Number of N-glycosylation sites observed in the crystal structure or predicted by the NetNGlyc server 1.0 in parentheses (http://www.cbs.dtu.dk/services/NetNGlyc/)