. Author manuscript; available in PMC: 2012 Apr 12.

Published in final edited form as: Cancer Cell. 2011 Apr 12;19(4):441–455. doi: 10.1016/j.ccr.2011.03.002

Table 1.

Disease Spectrum Pdx1-Cre; Kras^G12D; p53^f/+ Mice With Heterozygous or Homozygous MMP7 Deletion

		Median Age at Death (wks)	Mean Tumor Size (cm)	Duo/Stomach obstruction	Biliary obstruction	LN Disease^*	Liver Mets^*
Pdx1-Cre; p53^f/+; MMP7 ^Het	Kras^G12D; (N=12)	27.5	1.6 ± 0.3	8.3%	8.3%	58.3%	66.7%
Pdx1-Cre; p53^f/+; MMP7^KO	Kras^G12D; (N=8)	30.5	1.0 ± 0.4	37.5%	12.5%	0%	12.5%

p < 0.05, by Chi-square