Figure 3.

Nigral changes in the levels of axonal proteins at 12 d after poly(I:C) injection. A, Anterograde transport motor proteins (KIF1A and KIF1B) were increased, whereas KIF3A, KIF17, and dynein were decreased. Levels of TDP-43 were increased. B, Optical densities of the individual bands were quantified using NIH ImageJ. Optical densities were normalized by the averaged value of GAPDH and expressed as percentage of vehicle-injected conditions. Data are shown as mean ± SEM. Vehicle, n = 9; poly(I:C), n = 10; *p < 0.05, **p < 0.01, unpaired t test.