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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Pathol. 2011;224(1):33–44. doi: 10.1002/path.2840

Figure 6.

Figure 6

Reactivity to vasoactive agents of the ascending aorta of 6- and 24-month-old Fbn1+/+ and Fbn1+/mgΔ. (A,B) 10μmol/L phenylephrine (PE). 24-month-old Fbn1+/mgΔ mice were pooled (A) or separated (B) in non-pathological and pathological group. Ach-induced vasorelaxation (10μmol/L phenylephrine + 10μmol/L acetylcholine) in non-pathological vessels is represented as the reversal of the PE-induced vasoconstriction, in percent (C). *Generally significant difference with the control value, independent of age. #Generally significant difference between Fbn1+/+ and Fbn1+/mgΔ mice, independent of age. n=3–6 per group.