Figure 2.
A diagram of the kinetic model for the FNR system. x1 – fnr mRNA, x2 – apoFNR and 2Fe-FNR, x3 – 4Fe-FNR, x6 – ClpXP protease, x7 – iron sulfur cluster assembly proteins (Isc), x8 – molecular O2. The nucleotide and amino acid pools are assumed to be well regulated, and their nearly constant values are implicitly accounted for by the apparent rate constants for transcription and translation (a conventional assumption). The fate of material lost from the system by degradation and/or dilution is not shown. [See Tolla & Savageau (2010) for further details]