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Inactivation of the BNST blunts activation of stress-induced reinstatement circuitry. Lidocaine-treated mice exhibit a blunted response to stress-induced reinstatement as indicated by a decrease in the number of Fos-positive cells within the VTA (a), CeA (b), and NAc core (c). No differences were seen between the groups within the NAc shell (d), prelimbic (e) or infralimbic (f) cortices, or the lateral hypothalamus (g). *p < 0.05, vehicle versus lidocaine.
